Sleep Apnea and Genetics in Silver Spring, MD

Discover The Cause of Your Sleep Apnea With Silver Spring Sleep Solutions

In recent years, researchers have been studying genetic factors that may influence the development of sleep apnea. There’s growing evidence that sleep apnea has a hereditary component and tends to run in families. At Silver Spring Sleep Solutions, Dr. Alice Bassford and her team are committed to helping patients fall asleep more easily and overcome the genetic factors that contribute to sleep apnea.

Call our sleep dentist in Silver Spring at (301) 593-5500 today to learn more about the causes of sleep apnea and how you can create a better night’s sleep with Silver Spring Sleep Solutions. We’re here for patients in Silver Spring, Kensington, Wheaton-Glenmont, Washington DC, and beyond. 

Personalized Sleep Apnea Treatment Near You With Dr. Bassford

Sleep apnea can silently disrupt your nights and leave you feeling drained during the day—but relief is available right here in Silver Spring. Dr. Bassford is one of the best sleep specialists in Silver Spring, MD, and she is here to help. She provides expert care with a focus on comfort, offering custom sleep treatment options, including custom oral appliance therapy as a gentle, effective alternative to CPAP machines. These discreet devices are designed to keep your airway open, helping you breathe freely and sleep soundly through the night. At Silver Spring Sleep Solutions, your treatment is built around your needs, goals, and lifestyle. Let us help you take back your nights—and your energy.

What Is Sleep Apnea? Our Silver Spring Sleep Dentist Explains

Sleep apnea is a common sleep disorder characterized by repeated pauses in breathing throughout the night. These breathing interruptions can last 10 seconds or longer and can occur up to hundreds of times per night, preventing the body and brain from getting enough oxygen. This chronic lack of oxygen leads to poor sleep quality, excessive daytime sleepiness, and an increased risk of other medical conditions like high blood pressure, heart disease, and stroke.

While there are different types of sleep apnea, obstructive sleep apnea (OSA) is the most prevalent. OSA occurs when the muscles in the throat relax during sleep, causing soft tissue to collapse and block the airway. The brain senses this lack of breathing and briefly awakens the body to reopen the airway. These multiple awakenings prevent you from reaching the deeper, more restorative stages of sleep.

How Genetics Influence Sleep Apnea Risk Near Kensington, MD

While sleep apnea can affect people of all ages and backgrounds, research shows that you’re at an increased risk of developing the disorder if you have family members with sleep apnea. Having a first-degree relative with OSA, such as a parent, sibling, or child, raises your risk two to four times compared to the general population. The more closely related the family member, the higher your risk.

Specific Genes Linked to Sleep Apnea

In the last decade, researchers have identified variations in several genes that appear to be associated with the development of OSA. Some of the key genes implicated so far include:

  • ANGPT2
  • TNFα
  • PTGER3
  • LPAR1
  • GPR83
  • ARRB1
  • DRD1
  • HTR2A

While additional research is still needed, these discoveries are an important step in determining who may be genetically predisposed to OSA. This could lead to earlier diagnosis and treatment opportunities in high-risk individuals.

Genetic Traits That Contribute To Sleep Apnea

While sleep apnea is a complex disorder caused by multiple factors, researchers have identified some specific genetic traits that appear to raise the risk of developing OSA:

  • Smaller Upper Airway: Gene variants linked to having a narrow throat or mouth opening make it easier for tissues to obstruct breathing during sleep.
  • Enlarged Tonsils/Adenoids: Genes regulating tissue growth may lead to oversized tonsils and adenoids that block the airway.
  • Low Muscle Tone: Genetic mutations that cause hypotonia (low muscle tone) in the throat can contribute to airway collapse.
  • Brain Signaling Deficits: Variants in genes that control breathing regulation and arousal response may impair normal respiration control and airway opening during sleep apnea episodes.
  • Vascular Abnormalities: Genes affecting vascular health may lead to swelling, inflammation, and excess fluid in upper airway tissues.
  • Craniofacial Structure: Skeletal and dental genetic factors may produce smaller sinus/nasal cavities or misalignment that crowd the airway space.

These genetic differences make the upper airway more prone to becoming obstructed during sleep, leading to apnea and hypopnea events. While not fully determinative, identifying people with these high-risk traits could improve the prediction of OSA susceptibility.

Frequently Asked Questions

Is sleep apnea genetic?

Yes, there is a genetic component to sleep apnea. Those with a family member who has OSA are up to 4 times more likely to develop the disorder themselves. Specific genetic variants that can increase risk have also been identified.

Does sleep apnea run in families?

Sleep apnea does tend to run in families. The close association is likely due to hereditary factors that can predispose people to anatomical vulnerabilities, like having a smaller airway. Sleep apnea has higher rates of occurrence among close relatives.

Can you be born with sleep apnea?

It is very rare for infants to be born with sleep apnea. However, babies can develop OSA early due to enlarged tonsils, allergies, neuromuscular disorders, or anatomical defects of the airway present at birth. There are some genetic disorders tied to congenital forms of OSA as well.

If I have sleep apnea, will my children get it?

Having sleep apnea does increase the chances that your children will develop the disorder, but it is not a guarantee. The exact inheritance pattern is unknown, but estimates suggest a two to four times higher risk if a parent has OSA. Lifestyle factors like weight and hormone changes also influence OSA development later in life.

Explore the Cause of Your Sleep Apnea

While sleep apnea can affect anyone, research demonstrates that genetic factors play a role in OSA development. There are likely multiple genes that may contribute to someone’s risk. As our understanding of sleep apnea genetics improves, this could allow for specialized early interventions, treatment advancements, and even personalized medicine approaches tailored to an individual’s genetic profile.

If sleep apnea runs in your family, be proactive about your health by getting screened for symptoms. Diagnosis and effective treatment can greatly reduce your risk of complications and help you achieve restful sleep. Contact our Silver Spring dental office at (301) 593-5500 to discuss your risk factors, including any family history, to determine the best solutions for your health. We’re here for patients in Silver Spring, Kensington, Wheaton-Glenmont, Washington DC, and beyond. 

PHONE

OFFICE

10301 Georgia Ave, Suite 207
Silver Spring, MD 20902